The women's winners have been quite successful at WrestleMania. Royal Rumble victors are 5-2 − a 71.4% win percentage − in WrestleMania matches with two straight wins. Here is the history of what women's Royal Rumble winners did at WrestleMania:

Uso eliminating John Cena to win the men’s Royal Rumble at Lucas Oil Stadium on Saturday in theory secures him a main event spot at WrestleMania 41. But it also means either he, Roman Reigns, Cena or CM Punk could be out of a coveted main event spot of the two-night event.