1 Department of Neurology, Medical Centre Haaglanden, The Hague, The Netherlands 2 Department of Neurology, Maasstad Hospital, Rotterdam, The Netherlands 3 Department of Radiology, Medical Centre ...

The past few decades have seen growing interest in the neuropsychiatric syndrome of apathy, conceptualised as a loss of motivation manifesting as a reduction of goal-directed behaviour. Apathy occurs ...

4 Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden Background Alzheimer's disease (AD) ...

Objective To perform a systematic review of cases reported in the literature in which a peripheral trauma preceded the onset of a movement disorder (MD). Methods Two reviewers independently searched ...

3 UK Dementia Research Institute at Edinburgh, The University of Edinburgh, Edinburgh, UK 4 The Usher Institute, The University of Edinburgh, Edinburgh, UK Background Inflammatory responses to ...

Background Deep brain stimulation (DBS) of the globus pallidus interna (GPi) is a highly efficacious treatment for cervical dystonia, but its mechanism of action is not fully understood. Here, we ...

2 NIHR Biomedical Research Centre, Guy's & St. Thomas’ NHS Foundation Trust and King's College London, London, UK 3 Farr Institute of Health Informatics, University College London, London, UK 4 ...

Objective To test the hypothesis that imaging signs of ‘brain frailty’ and acute ischaemia predict clinical outcomes and symptomatic intracranial haemorrhage (sICH) after thrombolysis for acute ...

Background Total bilirubin (TBIL) has antioxidant and anti-inflammatory properties. This study aimed to determine whether elevated TBIL could modify the association between diabetes and stroke. Method ...

Correspondence to: Dr E H Reynolds, Institute of Epileptology, Weston Education Centre, King's College Denmark Hill Campus, Cutcombe Road, London SE5 9PJ, UK During three decades of neurological ...

Objective Persistent difficulty in using the upper limb remains a major contributor to physical disability post-stroke. There is a nihilistic view about what clinically relevant changes are possible ...

OBJECTIVES Increased resistance to stretch of muscles after stroke may be the result of centrally mediated neural factors such as spasticity or local, peripheral factors such as muscle contracture or ...